Why is it different when States do it?

If you listen to the Republicans lately, it sounds that an intrusive law from the federal government is orders of magnitude worse than the same law from a state.  If there's a law that mandates what my wife does with her lady parts, I really don't care whether its a federal law or whether its a state law, it's going to piss me off either way.  I suppose the one advantage of it being a state law is that I can move to a more civilized state, but that's only really an option for me because we are well educated and wealthy.  For most of the people who have no real option to move across the country, an invasive state law is no better than an invasive federal one.